Malaria Journal | |
Correlates of HIV and malaria co-infection in Southern India | |
关键词: Plasmodium vivax; Plasmodium falciparum; Malaria; HIV; Co-infection; Malaria antibody; Retrospective test; | |
DOI : 10.1186/1475-2875-11-306 | |
来源: DOAJ |
【 摘 要 】
Abstract
Background
Malaria and HIV co-infection adversely impact the outcome of both diseases and previous studies have mostly focused on falciparum malaria.
Methods
HIV-infected subjects (n=460) were randomly selected from the 4,611 individuals seen at a Voluntary Counseling and Testing Center in Chennai, India between Jan 2 to Dec 31 2008. Malaria testing was performed on stored plasma samples by nested PCR using both genus-specific and species-specific primers and immunochromatography-based rapid diagnostic test for detecting antibodies against
Results
Recent malaria co-infection, defined by the presence of antibodies, was detected in 9.8% (45/460) participants.
Conclusions
Retrospective testing of stored plasma samples for malaria antibodies can facilitate identification of populations with high rates of co-infection, and in this southern India HIV-infected cohort there was a considerable burden of malaria co-infection, predominantly due to
【 授权许可】
Unknown