A successful therapy for severe malaria accompanied by malaria-related acute kidney injury (MAKI) complications: a case report

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Syahputra, A.^1 ; Siregar, M.L.^2 ; Jamil, K.F.^2

Department of Internal Medicine, Syiah Kuala University Medical School, Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia^1

Department of Internal Medicine, Division of Tropical and Infectious Diseases, Syiah Kuala University Medical School, Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia^2

关键词: Aceh , Indonesia;    Black water;    Blood smears;    Case reports;    Dihydroartemisinin;    Hospital admissions;    Incidence rate;    Plasmodium vivax;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012069/pdf
DOI  :  10.1088/1755-1315/125/1/012069

来源: IOP

【 摘 要 】

Indonesia is an endemic malaria country with high levels of morbidity and mortality. In Aceh, by the end of 2016, based on the data from Annual Parasite Incidence, the incidence rate was 0.1 per 1.000 population at risk of malaria. One of severe malaria complications is malaria-related acute kidney injury(MAKI). The death increasesthreefold by the presence of MAKI. A 56 years old male farmer was a resident in Buketmeuh village, Meukek, South Aceh, Indonesia, which was an endemic malaria area. He hadfever for seven days, chills, sweating, joint pain, headache, nausea, vomit, yellow eyes and raved. Concentrated tea-colored urineduring four days before hospital admission with a small amount of urine of 200 cc in 24 hours. The diagnosis established based on the Plasmodium vivax trophozoite finding in the blood smear examination, and the severe malaria clinical descriptions such as black water fever (BWF)with MAKI complications. Artemether injection therapy followed by oral primaquine, dihydroartemisinin and piperaquine phosphate (DHP) and hemodialysis provide a good outcome.