Metabolomics Reveals the Effects of High Dietary Energy Density on the Metabolism of Transition Angus Cows

Animals

Simujide Huasai¹  Hao Chen¹  Aorigele Chen¹  Chunjie Wang² 

[1] College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China;College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China;

关键词: cow;    dietary energy density;    plasma;    negative energy balance;    metabolic profiles;   

DOI  :  10.3390/ani12091147

来源: DOAJ

【 摘 要 】

The diet energy level plays a vital role in the energy balance of transition cows. We investigated the effects of high dietary energy density on body metabolism. Twenty multiparous Angus cows were randomly assigned to two treatment groups (10 cows/treatment), one receiving a high-energy (HE) diet (NEm = 1.67 Mcal/kg of DM) and the other administered a control (CON) diet (NEm = 1.53 Mcal/kg of DM). The results indicated that feeding a high-energy diet resulted in higher plasma glucose concentration and lower concentrations of plasma NEFA and BHBA on d 14 relative to calving in the HE-fed cows compared to the CON-fed ones. The postpartum plasma levels of T-AOC were lower in cows that received the CON diet than in cows in the HE group, while the concentration of malondialdehyde (MDA) showed an opposite trend. Among the 51 significantly different metabolites, the concentrations of most identified fatty acids decreased in HE cows. The concentrations of inosine, glutamine, and citric acid were higher in HE-fed cows than in CON-fed cows. Enrichment analysis revealed that linoleic acid metabolism, valine, leucine as well as isoleucine biosynthesis, and glycerophospholipid metabolism were significantly enriched in the two groups.

【 授权许可】

Unknown