Imaging zebrafish neural circuitry from whole brain to synapse

Frontiers in Neural Circuits

Gordon X Wang¹  Louis Leung¹  Philippe Mourrain¹ 

[1] Stanford University;

关键词: Psychiatry;    Zebrafish;    calcium imaging;    whole brain imaging;    Clinical Neuroscience;    array tomography;   

DOI  :  10.3389/fncir.2013.00076

来源: DOAJ

【 摘 要 】

Recent advances in imaging tools are inspiring zebrafish researchers to tackle ever more ambitious questions in the neurosciences.Behaviorally fundamental conserved neural networks can now be potentially studied using zebrafish from a brain wide scale to molecular resolution.In this perspective, we offer a roadmap by which a zebrafish researcher can navigate the course from collecting neural activities across the brain associated with a behavior, to unraveling molecular identities and testing the functional relevance of active neurons, in order to reach important conclusions on how neural networks result in behaviors and changes in synaptic connectivity.

【 授权许可】

Unknown