Magnetic Nanoparticles—A Multifunctional Potential Agent for Diagnosis and Therapy

Cancers

Sonu Gandhi¹  Jahangeer Ahmed²  SaadM. Alshehri²  Norah Alhokbany²  RaghurajSingh Chouhan³  Milena Horvat³ 

[1] Amity Institute of Biotechnology, Amity University, Noida 201301, India;Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia;Department of Environmental Sciences, Jožef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia;

关键词: iron oxide nanoparticles;    cancer;    superparamagnetism;    tumor microenvironment;    magnetic nanoparticles;   

DOI  :  10.3390/cancers13092213

来源: DOAJ

【 摘 要 】

Magnetic nanoparticles gained considerable attention in last few years due to their remarkable properties. Superparamaganetism, non-toxicity, biocompatibility, chemical inertness, and environmental friendliness are some of the properties that make iron oxide nanoparticles (IONPs) an ideal choice for biomedical applications. Along with being easily tuneable and a tailored surface for conjugation of IONPs, their physio-chemical and biological properties can also be varied by modifying the basic parameters for synthesis that enhances the additional possibilities for designing novel magnetic nanomaterial for theranostic applications. This review highlights the synthesis, surface modification, and different applications of IONPs for diagnosis, imaging, and therapy. Furthermore, it also represents the recent report on the application of IONPs as enzyme mimetic compounds and a contrasting agent, and its significance in the field as an anticancer and antimicrobial agent.

【 授权许可】

Unknown