Diagnosis of COVID-19: facts and challenges

New Microbes and New Infections

H.H. Zalzala¹ 

[1] H. H. Zalzala, Department of Microbiology and Immunology, HLA Typing Research Unit, University of Baghdad Al-Kindy College of Medicine, Near al-Nahda Square, Baghdad, Iraq.;

关键词: COVID-19;    CRISPR;    ELISA;    LAMP;    lateral flow immunoassay;    PCR;   

DOI  :  

来源: DOAJ

【 摘 要 】

At the end of 2019, the novel coronavirus disease 2019 (COVID-19) emerged in Wuhan, China, then spread rapidly across the country and throughout the world. The causative agent is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); according to the International Committee on Taxonomy of Viruses, this virus has a nucleic acid sequence that is different from other known coronaviruses but has some similarity to the beta coronavirus identified in bats. Coronaviruses are a large virus group of enveloped positive-sense single-stranded RNA. They are divided into four genera—alpha, beta, delta and gamma—and alpha and beta coronaviruses are known to infect humans. Rapid and early diagnosis of COVID-19 is a challenging issue for physicians and other healthcare personnel. The sensitivity and specificity of the clinical, radiologic and laboratory tests used to diagnose COVID-19 are variable and largely differ in efficacy depending on the disease's stage of presentation.

【 授权许可】

Unknown