Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi

Revista da Sociedade Brasileira de Medicina Tropical

Z. Brener¹  O. Genaro²  P.M.Z. Coelho³ 

[1] Fundação Oswaldo Cruz;Instituto Nacional de Pesquisas da Amazônia;Universidade Federal de Minas Gerais;

关键词: Schistosoma mansoni;    Imunodepressão;    Granuloma;    Trypanosoma cruzi;   

DOI  :  10.1590/S0037-86821986000100008

来源: DOAJ

【 摘 要 】

Infection by Trypanosoma cruzi in mice depresses hepatic granuloma formation around Schistosoma mansoni eggs. This immunodepressive effect occurred in mice with Chagas' disease at the acute and/or chronic phases, granulomas being signijicantly smaller than those in Controls. Data suggest that Chagas ' disease depresses the delayed hypersensitivity immune response directly.

【 授权许可】

Unknown