Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi

Revista da Sociedade Brasileira de Medicina Tropical

FIOCRUZ, Belo Horizonte¹  Genaro, O.¹  UFMG, Belo Horizonte¹  Coelho, P.M.Z.¹  INPA, Manaus¹  Brener, Z.¹ 

关键词: Schistosoma mansoni;    Immunodepression;    Granuloma;    Trypanosoma cruzi;   

DOI  :  10.1590/S0037-86821986000100008

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Infection by Trypanosoma cruzi in mice depresses hepatic granuloma formation around Schistosoma mansoni eggs. This immunodepressive effect occurred in mice with Chagas' disease at the acute and/or chronic phases, granulomas being signijicantly smaller than those in Controls. Data suggest that Chagas ' disease depresses the delayed hypersensitivity immune response directly.

【 授权许可】

Unknown