Schistosoma mansoni: immunodepression of hepatic schistosome granuloma formation in mice infected by Trypanosoma cruzi

Revista da Sociedade Brasileira de Medicina Tropical

O. Genaro²  Z. Brener¹  P.m.z. Coelho¹ 

[1] ,INPA Departamento de Patologia Tropical Manaus

关键词: Schistosoma mansoni;    Immunodepression;    Granuloma;    Trypanosoma cruzi;    Schistosoma mansoni;    Imunodepressão;    Granuloma;    Trypanosoma cruzi;   

DOI  :  10.1590/S0037-86821986000100008

来源: SciELO

【 摘 要 】

Infection by Trypanosoma cruzi in mice depresses hepatic granuloma formation around Schistosoma mansoni eggs. This immunodepressive effect occurred in mice with Chagas' disease at the acute and/or chronic phases, granulomas being signijicantly smaller than those in Controls. Data suggest that Chagas ' disease depresses the delayed hypersensitivity immune response directly.

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