Acetamide Derivatives with Antioxidant Activity and Potential Anti-Inflammatory Activity

Molecules

关键词: amides;    antioxidant;    antiproliferative activity;    brine shrimp test;   

DOI  :  10.3390/molecules15032028

来源: DOAJ

【 摘 要 】

This study reports the synthesis and antioxidant activity of some new acetamide derivatives. The compounds’ structures were elucidated by NMR analysis and their melting points were measured. The in vitro antioxidant activity of these compounds was tested by evaluating the amount of scavenged ABTS radical and estimating ROS and NO production in tBOH- or LPS-stimulated J774.A1 macrophages. All compounds were tested for their effect on cell viability by an MTT assay and by a Brine Shrimp Test.

【 授权许可】

Unknown