Prediabetes is associated with poor functional outcome in patients with intracerebral hemorrhage

Brain and Behavior

Fei Chen¹  Pinglang Hu²  Xiaoqian Luan²  Guiqian Huang²  Jincai He²  Wenwei Ren²  ChengYe Zhou²  Qiongzhang Wang² 

[1] Department of Neurology The Deqing People's Hospital Huzhou Zhejiang China;Department of Neurology The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang China;

关键词: diabetes mellitus;    functional outcome;    intracerebral hemorrhage;    prediabetes;   

DOI  :  10.1002/brb3.1530

来源: DOAJ

【 摘 要 】

Abstract Introduction The association between prediabetes and functional outcome in cerebrovascular diseases is controversial. No study has explored the relationship between prediabetes and functional outcome in intracerebral hemorrhage patients. Our study aimed to explore the association between prediabetes and functional outcome in intracerebral hemorrhage patients 1 month poststroke. Methods One hundred and fifty intracerebral hemorrhage patients were consecutively recruited within the first 24 hr after admission and were followed up for 1 month. Patients were divided into a diabetes mellitus group, a prediabetes group, and a nondiabetic group by fasting glucose levels, 2‐hr postprandial blood glucose levels, and glycosylated hemoglobin levels. Patients with modified Rankin Scale scores >2 at 1 month were defined as having a poor functional outcome. Results The prediabetes group had a higher risk of poor functional outcome than the nondiabetic group in intracerebral hemorrhage patients (37.9% vs. 9.8%, χ2 = 11.521, p = .001). According to the logistic regression analyses, prediabetes was associated with a poor functional outcome in intracerebral hemorrhage patients after adjusting for confounding factors (odds ratio = 6.167, 95% confidence interval = 1.403–27.102, p = .016). Conclusions Our findings show that prediabetes is associated with a poor functional outcome in intracerebral hemorrhage patients 1 month poststroke.

【 授权许可】

Unknown