Synthesis of graphene quantum dots and their applications in drug delivery

Journal of Nanobiotechnology

Ming Zhang¹  Mohsen Mohammadniaei¹  Johan Liu²  Ya Liu²  Yifeng Fu²  Lilei Ye³  Nan Wang³  Fan Wang⁴  Changhong Zhao⁴  Qiqing Zhang⁴  Lu Li⁴  Xuebin Song⁴ 

[1] Department of Health Technology, Technical University of Denmark;Electronics Materials and Systems Laboratory, Department of Microtechnology and Nanoscience, Chalmers University of Technology;SHT Smart High-Tech AB;School of Life Sciences and Technology, Xinxiang Medical University;

关键词: Graphene quantum dots;    Top-down;    Bottom-up;    Drug delivery;    Delivery-release mode;   

DOI  :  10.1186/s12951-020-00698-z

来源: DOAJ

【 摘 要 】

Abstract This review focuses on the recent advances in the synthesis of graphene quantum dots (GQDs) and their applications in drug delivery. To give a brief understanding about the preparation of GQDs, recent advances in methods of GQDs synthesis are first presented. Afterwards, various drug delivery-release modes of GQDs-based drug delivery systems such as EPR-pH delivery-release mode, ligand-pH delivery-release mode, EPR-Photothermal delivery-Release mode, and Core/Shell-photothermal/magnetic thermal delivery-release mode are reviewed. Finally, the current challenges and the prospective application of GQDs in drug delivery are discussed.

【 授权许可】

Unknown