Oxidative stress and immune cell activation quantification in sepsis and non-sepsis critical care patients by neopterin/7,8-dihydroneopterin analysis

Pteridines

Shaw Geoff¹  Moltchanova Elena²  Carr Anitra³  Chambers Stephen³  Gaddam Ravinder Reddy⁴  Baxter-Parker Gregory⁵  Gieseg Steven P.⁵ 

[1] Department of Intensive Care, Christchurch Hospital, New Zealand;Department of Mathematics and Statistics, University of Canterbury, Christchurch, New Zealand;Department of Pathology & Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand;Division of Cardiovascular Medicine, Department of Internal Medicine, Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA;School of Biological Sciences, University of Canterbury, Christchurch, New Zealand;

关键词: sepsis;    neopterin;    7,8-dihydroneopterin;    kidney function;    inflammation;    biomarkers;   

DOI  :  10.1515/pteridines-2020-0015

来源: DOAJ

【 摘 要 】

Introduction: Neopterin and 7,8-dihydroneopterin are used as biomarkers of oxidative stress and inflammation, but the effect of kidney function on these measurements has not been extensively explored. We examine the levels of oxidative stress, inflammation and kidney function in intensive patients and compare them to equivalent patients without sepsis.

【 授权许可】

Unknown