Simultaneous oral administration of Salmonella Infantis and S. Typhimurium in chicks

Irish Veterinary Journal

Satoshi Murakami¹  Daisuke Onozuka²  Shuji Fujimoto³  Nobuyuki Sera⁴  Eriko Maeda-Mitani⁴  Tamie Noda⁴  Koichi Murakami⁵  Hirokazu Kimura⁵ 

[1] Department of Animal Science, Tokyo University of Agriculture;Department of Health Care Administration and Management, Kyushu University Graduate School of Medical Sciences;Department of Health Sciences, Faculty of Medical Sciences, Kyushu University;Fukuoka Institute of Health and Environmental Sciences;Infectious Disease Surveillance Center, National Institute of Infectious Diseases;

关键词: Salmonella infantis;    Salmonella typhimurium;    Chicken;    Basic reproductive rate;    Oral administration;    Chick bowel;   

DOI  :  10.1186/s13620-017-0105-x

来源: DOAJ

【 摘 要 】

Abstract Background To confirm the hypothesis that Salmonella enterica subspecies enterica serovar (S.) Infantis has higher basic reproductive rates in chicks compared with other Salmonella serovars, 1-day-old specific-pathogen-free chicks (n = 8) were challenged simultaneously with S. Infantis and S. Typhimurium per os. Challenged chicks (Group A) were then housed with non-infected chicks (Group B, n = 4) for 6 days (from 2 to 8 days of age). Group B birds were then housed with other non-infected birds (Group C, n = 4), which were then transferred to cages containing a further group of untreated chicks (Group D, n = 2). A control group consisting of four non-infected chicks was used for comparison. All chickens were humanely sacrificed at 18 days of age, and Salmonella from bowel and liver samples were enumerated. Results Both serovars were isolated from all groups except the control group. S. Typhimurium was isolated at a greater frequency than S. Infantis from the bowel samples of chicks from Groups B, C and D, while no differences in colonisation rates were observed between the two serovars in liver samples from Groups B, C and D. S. Typhimurium, but not S. Infantis, was immunohistochemically detected in the lamina propria of the cecum and rectum in five birds of Group A. Despite the competitive administration, neither of the two serovars completely excluded the other, and no differences were observed in basic reproductive rates between the two serovars. Conclusions These findings, together with data from previous studies, suggest that the initial quantitative domination of S. Infantis in chicken flocks may explain why this serovar is predominant in broiler chickens.

【 授权许可】

Unknown