Prospects and Opportunities for Microsystems and Microfluidic Devices in the Field of Otorhinolaryngology

Clinical and Experimental Otorhinolaryngology

Se Hwan Hwang¹  Alexander Revzin¹  Alan M. Gonzalez-Suarez¹  Gulnaz Stybayeva¹ 

[1] Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA;

关键词: microfluidics;    organoids;    in vitro diagnostics;    organ-on-a-chip;    otolaryngology;   

DOI  :  10.21053/ceo.2020.00626

来源: DOAJ

【 摘 要 】

Microfluidic systems can be used to control picoliter to microliter volumes in ways not possible with other methods of fluid handling. In recent years, the field of microfluidics has grown rapidly, with microfluidic devices offering possibilities to impact biology and medicine. Microfluidic devices populated with human cells have the potential to mimic the physiological functions of tissues and organs in a three-dimensional microenvironment and enable the study of mechanisms of human diseases, drug discovery and the practice of personalized medicine. In the field of otorhinolaryngology, various types of microfluidic systems have already been introduced to study organ physiology, diagnose diseases, and evaluate therapeutic efficacy. Therefore, microfluidic technologies can be implemented at all levels of otorhinolaryngology. This review is intended to promote understanding of microfluidic properties and introduce the recent literature on application of microfluidic-related devices in the field of otorhinolaryngology.

【 授权许可】

Unknown