Synthesis of some pyrazolone derivatives from ciprofloxacin and study of their cytotoxicity

Bangladesh Journal of Pharmacology

Hari Pado Devnath¹  Md. Rabiul Islam¹ 

[1] Department of Chemistry, Jahangirnagar University, Savar, Dhaka 1342;

关键词: Ciprofloxacin;    Cytotoxicity;    Pyrazolone;   

DOI  :  10.3329/bjp.v5i1.4693

来源: DOAJ

【 摘 要 】

Three pyrazolone derivativeswith pyrazole ring extensionwere synthesized from ciprofloxacin by treating the parent compound with hydrazine derivatives. All the products have been characterized by IR and 1H-NMR spectral analysis. These derivatives showed potential cytotoxicity against brine shrimp nauplii than the ciprofloxacin.

【 授权许可】

Unknown