Establishment and development of national community-based collaborative innovation demonstration areas to achieve the control target of hepatitis B in China

BMC Infectious Diseases

Xinghuo Pang¹  Zunyou Wu²  Yunde Hou²  Dexin Li²  Shuigao Jin²  Guojian Li³  Zizhao Li⁴  Fengcai Zhu⁵  Qing Li⁶  Peixin Wu⁶  Jinhui Gu⁶  Ruoqi Xing⁶  Di Gao⁶  Qun Meng⁷  Jianping Hu⁷  Hong Zhou⁷  Yuantao Hao⁸  Yude Chen⁸  Aiqiang Xu⁹  Zhengan Yuan^1,10  Wen Yang^1,11  Hong Tang^1,12  Mengfeng Li^1,13  Guangyu Zhang^1,14  Lin Zhou^1,15  Qiu Zhong^1,15  Wei Jiang^1,16  Yongping Yan^1,17  Jifang Sheng^1,18  Nanping Wu^1,18  Kaijin Xu^1,18  Ping Chen^1,18  Lanjuan Li^1,18  Chengbo Yu^1,18  Jingjing Ren^1,18  Tiansheng Xie^1,18  Chencheng Wang^1,18  Shigui Yang^1,18  Min Deng^1,18  Zhixin Yu^1,18  Yiping Li^1,18  Yanhong Zhao^1,18  Bing Ruan^1,18  Mingjian Ni^1,19  Lin Lu^2,20  Jun Yao^2,21 

[1] Beijing Center for Disease Control and Prevention;Chinese Center for Disease Control and Prevention;Guangxi Provincial Center for Disease Control and Prevention;Henan Provincial Center for Disease Control and Prevention;Jiangsu Provincial Center for Disease Control and Prevention;National Health and Family Planning Commission of China;National Statistical Information Center of China;Peking University;Shandong Provincial Center for Disease Control and Prevention;Shanghai Center for Disease Control and Prevention;Sichuan Provincial Center for Disease Control and Prevention;Sichuan University;Sun Yat-sen University;The 309th Hospital of PLA;The Center of Tuberculosis control of Guangdong Province;The Digital Medical and Health Technology Research Institute of Zhejiang Province;The Forth Military Medical University;The State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital of Zhejiang University, Zhejiang University School of Medicine;Xinjiang Provincial Center for Disease Control and Prevention;Yunnan Provincial Center for Disease Control and Prevention;Zhejiang Provincial Center for Disease Control and Prevention;

关键词: Community healthcare;    Hepatitis B;    Health policy;   

DOI  :  10.1186/s12879-019-4150-9

来源: DOAJ

【 摘 要 】

Abstract Background The major infectious diseases of hepatitis B has constituted an acute public health challenge in China. An effective and affordable HBV control model is urgently needed. A national project of Community-based Collaborative Innovation HBV (CCI-HBV) demonstration areas has optimized the existing community healthcare resources and obtained initial results in HBV control. Methods Based on the existing community healthcare network, CCI-HBV project combined the community health management and health contract signing service for long-staying residents in hepatitis B screening. Moreover, HBV field research strategy was popularized in CCI-HBV areas. After screening, patients with seropositive results were enrolled in corresponding cohorts and received treatment at an early stage. And the uninfected people received medical supports including health education through new media, behavior intervention and HBV vaccinations. In this process, a cloud-based National Information Platform (NIP) was established to collect and store residents’ epidemiological data. In addition, a special quality control team was set up for CCI project. Results After two rounds of screening, HBsAg positive rate dropped from 5.05% (with 5,173,003 people screened) to 4.57% (with 3,819,675 people screened), while the rate of new HBV infections was 0.28 per 100 person-years in the fixed cohorts of 2,584,322 people. The quality control team completed PPS sampling simultaneously and established the serum sample database with 2,800,000 serum samples for unified testing. Conclusions CCI-HBV project has established a large-scale field research to conduct whole-population screening and intervention. We analyzed the HBsAg prevalence and new infection rate of HBV in the fixed population for the epidemic trend and intervention effect. The purpose of CCI-HBV project is to establish and evaluate a practical model of grid management and field strategy, to realize the new goal to control hepatitis B in China. To provide policymakers with a feasible model, our results are directly applicable. Trial registration The project was funded by the Major Projects of Science Research for the 11th and 12th five-year plans of China, entitled “The prevention and control of AIDS, viral hepatitis and other major infectious diseases”, Grant Nos. 2009ZX10004901, 2011ZX10004901, 2013ZX10004904, 2014ZX10004007 and 2014ZX10004008.

【 授权许可】

Unknown