Kaohsiung Journal of Medical Sciences | |
HCV Infection Complicated with Nephrotic Syndrome, Immune Complex Crescentic Glomerulonephritis and Acute Renal Failure: A Case Report | |
Mei-Chuan Kuo1  Hung-Chun Chen1  Yung-Hsiung Lai1  Shang-Jyh Hwang1  Yi-Chun Chen1  | |
[1] Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University, Chun-Ho Memorial Hospital Kaohsiung, Taiwan; | |
关键词: HCV infection; HCV-associated autoimmune disease; nephrotic syndrome; crescentic glomerulonephritis; renal failure; | |
DOI : 10.1016/S1607-551X(09)70153-6 | |
来源: DOAJ |
【 摘 要 】
There is ample evidence suggesting that hepatitis C virus (HCV)-associated autoimmunity plays a role in a broad spectrum of autoimmune diseases, which are usually overlooked. We report on a case of nephrotic syndrome, palpable purpura, cryoglobulinemia, hypocomplementemia, and acute renal failure complicated by immune complex glomerulonephritis (GN). The patient is a 64-year-old man with HCV infection, who was initially considered to present only an HCV-associated cryoglobulinemic GN. However, renal biopsy revealed a “full house” immune complex crescentic GN, which led to our subsequent investigation. The attending clinicians faced what is a common dilemma, where an HCV-associated autoimmune disease inevitably switches to a lupus-like GN. Hence, we also discuss treatment.
【 授权许可】
Unknown