Long COVID-19 in Children: From the Pathogenesis to the Biologically Plausible Roots of the Syndrome

Biomolecules

Michele Ghezzi¹  Diego Peroni²  Pasquale Comberiati²  Maria Di Cicco²  Michele Piazza³  Luca Pecoraro³ 

[1] Allergology and Pneumology Unit, V. Buzzi Children’s Hospital, 20154 Milan, Italy;Department of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, 56126 Pisa, Italy;Department of Surgery, Dentistry, Pediatrics and Gynecology, University of Verona, 37126 Verona, Italy;

关键词: COVID-19;    SARS-CoV-2;    long-COVID;    vitamins;    antioxidant;    vitamin D;   

DOI  :  10.3390/biom12040556

来源: DOAJ

【 摘 要 】

Long Coronavirus disease-19 (COVID-19) refers to the persistence of symptoms related to the infection with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). This condition is described as persistent and can manifest in various combinations of signs and symptoms, such as fatigue, headache, dyspnea, depression, cognitive impairment, and altered perception of smells and tastes. Long COVID-19 may be due to long-term damage to different organs—such as lung, brain, kidney, and heart—caused by persisting viral-induced inflammation, immune dysregulation, autoimmunity, diffuse endothelial damage, and micro thrombosis. In this review, we discuss the potential and biologically plausible role of some vitamins, essential elements, and functional foods based on the hypothesis that an individual’s dietary status may play an important adjunctive role in protective immunity against COVID-19 and possibly against its long-term consequences.

【 授权许可】

Unknown