A review on hypersensitivity reactions to fungal aeroallergens in patients with allergic disorders in Iran

Current Medical Mycology

zeinab Nazari¹  Fatemeh Ahangarkani²  negar ghaffari³  javad Ghaffari⁴ 

[1] Department of Gynecology, Mazandaran University of Medical Sciences, Sari, Iran;Invasive Fungi Research Center, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran;Mazandaran University of Medical Sciences, Sari, Iran;Pediatric Infecious Diseases Research Center, Mazandaran University of Medical Sciences, Sari, Iran;

关键词: Allergic rhinitis;    Asthma;    Atopic dermatitis;    Fungus;    Mold;    Urticaria;   

DOI  :  

来源: DOAJ

【 摘 要 】

Fungal agents account for the clinical manifestation of allergic disorders. The aim of the present study was to review the prevalence of hypersensitivity reactions to fungal aeroallergens in patients with allergic disorders, including allergic rhinitis, asthma, urticaria, and eczema, in Iran. The initial literature search resulted in the identification of 50 records, 26 cases of which met the inclusion criteria. Regarding the methods adopted for the detection of fungal allergens, serum-specific IgE and skin prick tests were used in 6 and 20 studies, respectively. Aspergillus fumigatus and Alternaria alternata sensitization was the most common allergic sensitization among the patients with allergic disorders. According to the reviewed studies, despite the humid climate of the north of Iran, fungal sensitization has a prevalence range of 5-70% in this region. In other regions, such as central and southern Iran, which have a dry and warm climate, fungal sensitization reportedly has a prevalence range of 5-65%. The prevalence of fungal sensitizations varies in different allergic disorders due to the factors related to geographic and genetic issues, gender, sample size, test operator, and assessment method.

【 授权许可】

Unknown