Case report of recurrent anaplastic oligodendroglioma with mixed astrocytic components and pathological discordance of tumor progression

Interdisciplinary Neurosurgery

C. Strauss¹  J. Prell²  M. Scheer³  C. Scheller³  C. Kubelt³  M. Skalej⁴  C. Mawrin⁵ 

[1] Corresponding author at: Department of Neurosurgery, University Hospital Halle, Ernst-Grube-Straße 40, 06120 Halle, Germany.;Department of Neuropathology, University Magdeburg, Leipziger Strasse, 44, 39120 Magdeburg, Germany;Department of Neurosurgery, University Hospital Halle, Ernst-Grube-Straße 40, 06120 Halle, Germany;Department of Neurosurgery, University Hospital Kiel, Arnold-Heller-Straße 3, 24105 Kiel, Germany;Department of Radiology, University Hospital Halle, Ernst-Grube-Straße 40, 06120 Halle, Germany;

关键词: Oligoastrocytoma;    Diffuse glioma;    Recurrence;    Brain tumor;    Molecular feature;   

DOI  :  

来源: DOAJ

【 摘 要 】

We present a case of a patient with the initial diagnosis of oligoastrocytoma WHO grade II. After multiple previous treatments and transformation to an anaplastic oligoastrocytoma WHO grade III, imaging after radiotherapy showed another tumor progression. Histopathological analysis after tumor resection confirmed parts of an astrocytic and an oligodendroglial tumor with extensive therapy-related changes. This constellation is not sufficiently covered by the current classification system and currently described as a diffuse glioma.

【 授权许可】

Unknown