Prolinethioamides versus Prolinamides in Organocatalyzed Aldol Reactions—A Comparative Study

Symmetry

卷:3

关键词: organocatalysis;    prolinethioamides;    prolinamides;    aldol reaction;    enamine-iminium catalysis;   

DOI  :  10.3390/sym3020265

来源: DOAJ

【 摘 要 】

Various organocatalysts have been developed for the aldol reaction but particular attention has been paid to prolinamide derivatives. They are easy to prepare and their catalytic activity can be readily tuned through structural modification. In this review, the comparison of catalytic activities between prolinethioamides and their respective amides in direct asymmetric aldol reactions is presented.

【 授权许可】

Unknown