期刊论文详细信息
Journal of Pediatric and Neonatal Individualized Medicine 卷:8
Childhood sacrococcygeal teratoma: a clinicopathological study
Kamal Nain Rattan1  Hemant Yadav2  Divya Srivastava2  Ananta Rattan3 
[1] Department of Paediatric Surgery, PGIMS, Rohtak, Haryana, India;
[2] Department of Pathology, PGIMS, Rohtak, Haryana, India;
[3] Department of Pediatrics, RNT Medical College, Udaipur, Rajasthan, India;
关键词: sacrococcygeal teratoma;    children;    mature;    immature;    malignancy;    tumor marker;   
DOI  :  10.7363/080116
来源: DOAJ
【 摘 要 】

Background: Sacrococcygeal teratoma (SCT) is a relatively uncommon tumor affecting neonates, infants, and children with a female preponderance. Age is an important predictor of malignancy in SCT. Early antenatal diagnosis influences the management and provides a better outcome.Aim: The present study was carried out to describe in detail various clinicopathological features and outcome of SCT patients; as many reports are available from the West, there is a paucity of literature on this entity from the Eastern region, especially India, which has a unique socioeconomic and demographic background.Materials and methods: The study included 52 patients of SCT operated for 16 years from 2000 to 2015. A retrospective review of various parameters was done from the medical case records available in the Department of Pediatric Surgery (PGIMS, Rohtak, Haryana, India).Result: There were 40 females and 12 males with age ranging from newborn to 13 years. Thirty-three children (63%) presented in the neonatal age group. There were 40 cases of benign (mature), 7 immature and 5 malignant teratomas. Four cases had a recurrence on follow-up. Out of 52 patients, 7 died while the others are doing well on follow-up.Conclusion: A prenatal diagnosis of SCT is essential for reducing morbidity and mortality. Delayed presentation and the presence of malignant changes continue to be poor prognostic factors. Strict follow-up by clinical examination, ultrasound and tumor markers is mandatory to look for any recurrence.

【 授权许可】

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