An Uncommon Recurrent Metastasis of Ovarian Immature Teratoma to the Small Bowel

Case Reports in Oncology

Tareq Saleh¹  Omar Bani Hani²  Mohammad Al‐hazaimeh³  Tamara Smadi³  Mahmoud Jaradat³  Ruba Shannaq⁴  Mohammed El-Sadoni⁵  Nisreen Abu Shahin⁵  Ahmad Alhesa⁵ 

[1] Department of Basic Medical Sciences, Faculty of Medicine, The Hashemite University, Zarqa, Jordan;Department of Diagnostic Radiology, Al-Bashir Hospital, Ministry of Health, Amman, Jordan;Department of General Surgery, Jordanian Royal Medical Services, Amman, Jordan;Department of Pathology, King Hussein Medical Center, Royal Medical Service, Amman, Jordan;Department of Pathology, Microbiology and Forensic Medicine, School of Medicine, The University of Jordan, Amman, Jordan;

关键词: mature;    immature;    teratoma;    metastasis;    small bowel;   

DOI  :  10.1159/000520950

来源: DOAJ

【 摘 要 】

Immature ovarian teratomas are rare ovarian germ cell tumors associated with a variable potential of distant metastasis. The acquisition of mature phenotypes upon post-treatment recurrence of immature teratomas has been previously described. In this study, we report, for the first time, a rare case of a recurrent ovarian immature teratoma with mature deposits in the small bowel. An incidental pelvi-abdominal mass was identified in a 30-year-old pregnant patient during antenatal ultrasonography. The mass, which was resected through salpingo-oopherectomy, was histopathologically characterized as an immature teratoma of grade 2 and treated with 3 cycles of chemotherapy. After 3 years of completing treatment, the patient suffered from severe anemia which was investigated by capsule endoscopy that identified a bleeding source in the ileum. Imaging studies revealed an intrabdominal mass that was resected laparoscopically. The pathological assessment of the mass identified a submucosal/intramuscular teratoma with mature elements indicative of a recurrent metastasis of immature teratoma associated with post-chemotherapy retroconversion. The secondary mass was then managed with adjuvant chemotherapy.

【 授权许可】

Unknown