A New Approach for Indexing Honey for Its Heath/Medicinal Benefits: Visualization of the Concept by Indexing Based on Antioxidant and Antibacterial Activities

Medicines

卷:5

Anwar Rayan¹  Mahmoud Rayan¹  Saleh Abu-Lafi²  Mahmud Masalha³  Mouhammad Zeidan⁴  Basheer Abu-Farich⁵  Nael Issa⁶ 

[1] Drug Discovery Informatics Lab, QRC-Qasemi Research Center, Al-Qasemi Academic College, Baka El-Garbiah 30100, Israel;

[2] Faculty of Pharmacy, Al-Quds University, Abu-Dies 144, Palestine;

[3] Laboratory of Microbiology, QRC-Qasemi Research Center, Al-Qasemi Academic College, P.O. Box 124, Baka EL-Garbiah 30100, Israel;

[4] Molecular Genetics and Virology Laboratory, QRC-Qasemi Research Center, Al-Qasemi Academic College, P.O. Box 124, Baka EL-Garbiah 30100, Israel;

[5] QRC-Qasemi Research Center, Al-Qasemi Academic College, P.O. Box 124, Baka EL-Garbiah 30100, Israel;

[6] Science Education Department, Al-Qasemi Academic College, P.O. Box 124, Baka EL-Garbiah 30100, Israel;

关键词: honey;    antibacterial;    antifungal;    antioxidant;    free radical scavenging;    health benefits’ index;   

DOI  :  10.3390/medicines5040135

来源: DOAJ

【 摘 要 】

Background: The goals of the current study were to address a new concept termed a health benefits’ index (HBI) and to verify the type of correlation between the pricing of honey and its HBI/medicinal properties. Diverse types of honey from different origins and places were investigated for their antioxidant and antimicrobial activity. Methods: We have utilized a modified protocol of the DPPH assay for measuring free radical scavenging and the microdilution test for the determination of antibacterial/antifungal minimum inhibitory concentrations (MICs). MICs were determined against Staphylococcus aureus, Escherichia coli, Salmonella typhimurium, and Candida albicans microorganisms. Employing a “combined benefits approach„ enabled us to attach to each honey type a unique number of HBI that correlate with honey health and medicinal values. Results: The various types of honey demonstrated significant but variable antioxidant, antibacterial, and antifungal activities. Types of wildflower-labeled honey were found to have a wide range of HBI values and medicinal properties, probably due to their containing different nectar contents/phytochemicals. Moreover, an inconsiderable correlation was detected between the market prices of different types of honey and their HBIs. Conclusions: The proposed index of health benefits could be recalculated/updated following measurement of more and more medicinal properties, such as anti-inflammatory, antidiabetic, and anticancer activities. This index could be used as an effective tool for consumers of honey to evaluate the real value of the purchased product.

【 授权许可】

Unknown