Interaction between Insects, Toxins, and Bacteria: Have We Been Wrong So Far?

Toxins

卷:10

Guillaume Tetreau¹ 

[1] University of Perpignan, IHPE UMR 5244, CNRS, IFREMER, University of Montpellier, 66000 Perpignan, France;

关键词: invertebrate immunity;    host-pathogens interaction;    toxins;    Bacillus thuringiensis;    resistance;   

DOI  :  10.3390/toxins10070281

来源: DOAJ

【 摘 要 】

Toxins are a major virulence factor produced by many pathogenic bacteria. In vertebrates, the response of hosts to the bacteria is inseparable from the response to the toxins, allowing a comprehensive understanding of this tripartite host-pathogen-toxin interaction. However, in invertebrates, this interaction has been investigated by two complementary but historically distinct fields of research: toxinology and immunology. In this article, I highlight how such dichotomy between these two fields led to a biased, or even erroneous view of the ecology and evolution of the interaction between insects, toxins, and bacteria. I focus on the reason behind such a dichotomy, on how to bridge the fields together, and on confounding effects that could bias the outcome of the experiments. Finally, I raise four questions at the border of the two fields on the cross-effects between toxins, bacteria, and spores that have been largely underexplored to promote a more comprehensive view of this interaction.

【 授权许可】

Unknown