Propyl Gallate

Molbank

卷:2021

KieuOanh Ha¹  VanGiang Nguyen¹  MinhNgoc Le¹  VanHai Nguyen¹  NguyetSuong Huyen Dao¹  HoaBinh Nguyen¹  DinhLuyen Nguyen¹  ThaiHa Van Pham²  ThiHong Nguyen³  NguyenTrieu Trinh⁴ 

[1] Department of Pharmaceutical Industry, Hanoi University of Pharmacy, Hanoi 110403, Vietnam;

[2] Department of Traditional Pharmacy, Hanoi University of Pharmacy, Hanoi 110403, Vietnam;

[3] Laboratory for Establishment of Reference Standards, National Institute of Drug Quality Control, Hanoi 11022, Vietnam;

[4] School of Environmental and Life Sciences, College of Engineering, Science and Environment, University of Newcastle, NSW 2308, Australia;

关键词: antioxidant;    esterification;    potassium hydrogen sulfate;    propyl gallate;   

DOI  :  10.3390/M1201

来源: DOAJ

【 摘 要 】

The title compound, propyl gallate (III), is an important substance popularly used in the food, cosmetic and pharmaceutical industries. Current chemical syntheses of this compound are based on the acylation supported by thionyl chloride, DIC/DMAP or Fischer esterification using a range of homogenous and heterogenous catalysts. In this paper, an efficient, green, straightforward, and economical method for synthesizing propyl gallate using potassium hydrogen sulfate, KHSO₄, as the heterogenous acidic catalyst has been developed for the first time. In addition, this paper provides a comprehensive spectral dataset for the title compound, especially the new data on DEPT and 2D NMR (HSQC and HMBC) spectra which are not currently available in the literature.

【 授权许可】

Unknown