Perspectives on composite films of chitosan-based natural products (Ginger, Curcumin, and Cinnamon) as biomaterials for wound dressing

Arabian Journal of Chemistry

卷:15

Moustapha Eid Moustapha¹  Hala A. Ibrahium²  Nasser S. Awwad³  A.A. Menazea⁴  Ahmad El Askary⁵  Khadiga Ahmed Ismail⁵  M.O. Farea⁶ 

[1] Department of Semi Pilot Plant, Nuclear Materials Authority, P.O. Box 530, El Maadi, Egypt;

[2] Biology Department, Faculty of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia;

[3] Chemistry Department, Faculty of Science, King Khalid University, P.O. Box 9004, Abha 61413, Saudi Arabia;

[4] Department of Chemistry, College of Science and Humanities, Prince Sattam bin Abdulaziz University, Alkharj, Saudi Arabia;

[5] Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia;

[6] Department of Physics, Faculty of Science, IBB University, Yemen;

关键词: Chitosan;    Ginger;    Curcumin;    Cinnamon;    Antimicrobial Activity;   

DOI  :  

来源: DOAJ

【 摘 要 】

Natural materials are gaining popularity in wound healing and food applications, and they have the potential to alleviate the major environmental problems generated via traditional materials. Biomaterials based on Chitosan incorporated with natural products (Ginger, Curcumin, and Cinnamon) have been fabricated by solvent casting method. The antimicrobial characterization of the prepared samples were also investigated using in vitro antimicrobial studies using Gram-positive microorganism [Micrococcus luteus, Staphylococcus aureus, and Staphylococcus epidermidis], Gram-negative microorganism [Pseudomonas aeruginosa], and pathogenic [Candida albicans]. XRD patterns confirmed the complexation between chitosan and other natural products and this indicate the change in structural of chitosan. The shifting and disappearing of bands in FTIR-ATR and changing in fingerprints in FTIR spectra indicate the homogeneity and interaction between chitosan and the other. Optical properties such as absorption, absorption coefficient, Urbach tail and band gap calculation confirmed that Ginger, Curcumin and Cinnamon interact with chitosan and induces localized state between valence and conduction band. The mechanical properties also studied and revealed that Chitosan/Ginger has the best mechanical characteristic compared the other samples. In addition, the shifting toward higher wavelength for chitosan/Ginger may be utilized to generate electron–hole pairs, which is important for antimicrobial activities, and this confirmed from antimicrobial analysis that Chitosan/Ginger give high antimicrobial activity toward Gram-positive microorganism and suggest it for wound dressing application.

【 授权许可】

Unknown