Phages Preying on Bacillus anthracis, Bacillus cereus,and Bacillus thuringiensis: Past, Present and Future

Viruses

卷:6

Annika Gillis¹  Jacques Mahillon¹ 

[1] Laboratory of Food and Environmental Microbiology, Université catholique de Louvain,Croix du Sud 2, L7.05.12, B-1348 Louvain-la-Neuve, Belgium;

关键词: (bacterio)phages;    Bacillus cereus group;    Bacillus anthracis;    Bacillus thuringiensis;    transducing phages;    chromosomal prophages;    plasmidial prophages;    jumbo-phages;    Gamma-like phages;   

DOI  :  10.3390/v6072623

来源: DOAJ

【 摘 要 】

Many bacteriophages (phages) have been widely studied due to their major role in virulence evolution of bacterial pathogens. However, less attention has been paid to phages preying on bacteria from the Bacillus cereus group and their contribution to the bacterial genetic pool has been disregarded. Therefore, this review brings together the main information for the B. cereus group phages, from their discovery to their modern biotechnological applications. A special focus is given to phages infecting Bacillus anthracis, B. cereus and Bacillus thuringiensis. These phages belong to the Myoviridae, Siphoviridae, Podoviridae and Tectiviridae families. For the sake of clarity, several phage categories have been made according to significant characteristics such as lifestyles andlysogenic states. The main categories comprise the transducing phages, phages witha chromosomal or plasmidial prophage state, γ-like phages and jumbo-phages. The current genomic characterization of some of these phages is also addressed throughout this work and some promising applications are discussed here.

【 授权许可】

Unknown