Wound Healing with Electrical Stimulation Technologies: A Review

Polymers

卷:13

Yt Jun Cheah¹  Mohd Heikal Mohd Yunus¹  Muhamad Ramdzan Buyong² 

[1] Department of Physiology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur 56600, Malaysia;

[2] Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor, Malaysia;

关键词: electrical stimulation;    skin;    tissue engineering;    wound healing;   

DOI  :  10.3390/polym13213790

来源: DOAJ

【 摘 要 】

Electrical stimulation (ES) is an attractive field among clinicians in the topic of wound healing, which is common yet complicated and requires multidisciplinary approaches. The conventional dressing and skin graft showed no promise on complete wound closure. These urge the need for the exploration of electrical stimulation to supplement current wound care management. This review aims to provide an overview of electrical stimulation in wound healing. The mechanism of galvanotaxis related to wound repair will be reviewed at the cellular and molecular levels. Meanwhile, different modalities of externally applied electricity mimicking a physiologic electric field will be discussed and compared in vitro, in vivo, and clinically. With the emerging of tissue engineering and regenerative medicine, the integration of electroconductive biomaterials into modern miniaturised dressing is of interest and has become possible with the advancing understanding of smart biomaterials.

【 授权许可】

Unknown