Maternal Consumption of Milk or Dairy Products During Pregnancy and Birth Outcomes: A Systematic Review and Dose-Response Meta-Analysis

Frontiers in Nutrition

卷:9

Shanyan Gao¹  Qijun Wu²  Yang Xia²  Donghui Huang²  Chao Ji²  Huixu Dai²  Qing Chang²  Zhiying Zhao²  Xin Xu²  Hang Li²  Yuhong Zhao³ 

[1] Clinical Research Center, Shengjing Hospital of China Medical University, Shenyang, China;

[2] Department of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China;

[3] Key Laboratory of Precision Medical Research on Major Chronic Disease, Liaoning, China;

关键词: pregnant woman;    milk;    dairy;    fetal growth;    birth outcome;    dose-response meta-analysis;   

DOI  :  10.3389/fnut.2022.900529

来源: DOAJ

【 摘 要 】

PurposeThis study aimed to systematically review current evidence and quantitatively evaluate the associations between milk or dairy consumption during pregnancy and birth outcomes.MethodsThis systematic review had been reported in accordance with the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. A supplementary literature search in PubMed, Web of Science, Cochrane Library, and Embase was conducted on 30 March 2021. Studies that assessed the association of maternal consumption of milk or dairy with birth-related outcomes were identified. The dose-response meta-analyses of continuous data and categorical data were applied. One-stage approach and two-stage approach were used where appropriate.ResultsIn total, 42 studies were eligible for the present systematic review, and 18 of them were included in the outcome-specific meta-analyses. The dose-response meta-analysis [Number of studies (N) = 9] predicted a maximum mean change in birthweight of 63.38 g [95% Confidence Interval (CI) = 0.08, 126.67] at 5.00 servings per day. Intake of dairy products had the greatest protective effect on small for gestational age at a maximum of 7.2 servings per day [Relative risk (RR) = 0.69, 95% CI = 0.56, 0.85] (N = 7). The risk of large for gestational age was predicted to be maximum at 7.20 servings per day of dairy consumption, with the RR and 95% CI of 1.30 (1.15, 1.46; N = 4). In addition, the relationship between dairy consumption and low birth weight (RR = 0.70, 95% CI = 0.33, 1.50; N = 5) and pre-mature birth (RR = 1.13, 95% CI = 0.87, 1.47; N = 5) was not significant, respectively.ConclusionsMaternal consumption of dairy during pregnancy has a potential effect on fetal growth. Further well-designed studies are warranted to clarify the specific roles of individual dairy products.Systematic Review Registrationidentifier: PROSPERO 2020 CRD42020150608

【 授权许可】

Unknown