Dietary Sources of Vitamin B-12 and Their Association with Vitamin B-12 Status Markers in Healthy Older Adults in the B-PROOF Study

Nutrients

Elske M. Brouwer-Brolsma²  Rosalie A. M. Dhonukshe-Rutten²  Janneke P. van Wijngaarden²  Nikita L. van der Zwaluw²  Nathalie van der Velde¹ 

[1] Erasmus MC, Department of Internal Medicine, P.O. Box 2040, Rotterdam 3000 CA, The Netherlands; E-Mail:;Division of Human Nutrition, Wageningen University, P.O. Box 17, Wageningen 6700 AA, The Netherlands; E-Mails:

关键词: vitamin B-12 intake;    serum vitamin B-12;    dairy;    milk;    yoghurt;    cheese;    meat;    fish and shellfish;    eggs;   

DOI  :  10.3390/nu7095364

来源: mdpi

【 摘 要 】

Low vitamin B-12 concentrations are frequently observed among older adults. Malabsorption is hypothesized to be an important cause of vitamin B-12 inadequacy, but serum vitamin B-12 may also be differently affected by vitamin B-12 intake depending on food source. We examined associations between dietary sources of vitamin B-12 (meat, fish and shellfish, eggs, dairy) and serum vitamin B-12, using cross-sectional data of 600 Dutch community-dwelling adults (≥65 years). Dietary intake was assessed with a validated food frequency questionnaire. Vitamin B-12 concentrations were measured in serum. Associations were studied over tertiles of vitamin B-12 intake using P for trend, by calculating prevalence ratios (PRs), and splines. Whereas men had significantly higher vitamin B-12 intakes than women (median (25th–75th percentile): 4.18 (3.29–5.38) versus 3.47 (2.64–4.40) μg/day), serum vitamin B-12 did not differ between the two sexes (mean ± standard deviation (SD): 275 ± 104 pmol/L versus 290 ± 113 pmol/L). Higher intakes of dairy, meat, and fish and shellfish were significantly associated with higher serum vitamin B-12 concentrations, where meat and dairy—predominantly milk were the most potent sources. Egg intake did not significantly contribute to higher serum vitamin B-12 concentrations. Thus, dairy and meat were the most important contributors to serum vitamin B-12, followed by fish and shellfish.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.