Shorter Incubation Period among COVID-19 Cases with the BA.1 Omicron Variant

International Journal of Environmental Research and Public Health

卷:19

Chie Taniguchi¹  Yuki Takahashi²  Masaru Kinoshita²  Sanae Hattori³  Hitomi Nagai⁴  Tsuyoshi Ogata⁵  Hideo Tanaka⁶  Keisuke Matsubayashi⁷  Toshiyuki Shibata⁷ 

[1] College of Nursing, Aichi Medical University, Nagakute 480-1195, Japan;

[2] Fujiidera Public Health Center of Osaka Prefectural Government, Fujiidera 583-0024, Japan;

[3] Ibaraki Prefetural Office, Mito 310-0852, Japan;

[4] Ibaraki Public Health Center of Osaka Prefectural Government, Ibaraki 567-8585, Japan;

[5] Itako Public Health Center of Ibaraki Prefectural Government, Itako 311-2422, Japan;

[6] Public Health Center of Neyagawa City, Neyagawa 572-0838, Japan;

[7] Public Health Center of Suita City, Suita 564-0072, Japan;

关键词: SARS-CoV-2;    COVID-19;    Omicron variant;    incubation period;    Alpha variant;    Japanese Public Health Center;   

DOI  :  10.3390/ijerph19106330

来源: DOAJ

【 摘 要 】

We aimed to elucidate the range of the incubation period in patients infected with the SARS-CoV-2 Omicron variant in comparison with the Alpha variant. Contact tracing data from three Japanese public health centers (total residents, 1.06 million) collected following the guidelines of the Infectious Diseases Control Law were reviewed for 1589 PCR-confirmed COVID-19 cases diagnosed in January 2022. We identified 77 eligible symptomatic patients for whom the date and setting of transmission were known, in the absence of any other probable routes of transmission. The observed incubation period was 3.03 ± 1.35 days (mean ± SDM). In the log-normal distribution, 5th, 50th and 95th percentile values were 1.3 days (95% CI: 1.0–1.6), 2.8 days (2.5–3.1) and 5.8 days (4.8–7.5), significantly shorter than among the 51 patients with the Alpha variant diagnosed in April and May in 2021 (4.94 days ± 2.19, 2.1 days (1.5–2.7), 4.5 days (4.0–5.1) and 9.6 days (7.4–13.0), p < 0.001). As this incubation period, mainly of sublineage BA.1, is even shorter than that in the Delta variant, it is thought to partially explain the variant replacement occurring in late 2021 to early 2022 in many countries.

【 授权许可】

Unknown