Three-Component Reaction of Tautomeric Amidines with3-Ferrocenylmethylidene-2,4-pentanedione. Formation of Polymeric Coordination Complexes of PotassiumFerrocenyl-(hexahydro)pyrimidoxides

Molecules

卷:19

Irina P. Beletskaya¹  Tatiana Klimova²  Sandra Cortez Maya²  Marcos Flores-Alamo²  Elena I. Klimova² 

[1] Chemistry Department, Lomonosov Moscow State University, Leninskie Gory, Moscow119899, Russia;

[2] Facultad de Química, Universidad Nacional Autónoma de México, Cd. Universitaria, Coyoacán, C.P. 04510, México D.F., Mexico;

关键词: ferrocene;    3-ferrocenylmethylidene-2,4-pentanedione;    amidines;    ferrocenyl-pyrimidines;    ferrocenylpiperidones;    complexes of potassium ferrocenyl(hexahydro)-pyramidin-4-oxides;   

DOI  :  10.3390/molecules19010041

来源: DOAJ

【 摘 要 】

Acetamidine hydrochloride and p-aminobenzamidine dihydrochloride interact with 3-ferrocenylmethylidene-2,4-pentanedione at 80–82 °C in the presence of K2CO3 in the water–alcohol medium in two tautomeric forms (the amidoimine and enediamine ones) with formation of mixtures of pyrimidine and piperidone derivatives and polymeric coordination complexes of potassium ferrocenyl(hexahydro)pyrimidoxides. The structure of the resultant compounds is elucidated on the basis of IR, 1H- and 13C-NMR spectroscopy, mass spectrometry and elemental analysis data. The crystal structures of6-ferrocenyl-4-hydroxy-4-methyl-2-piperidone, potassium 6-ferrocenyl-4-methyl-2-methylidene(hexahydro)pyrimidin-4-oxide and 2-(4-aminophenyl)-4-ferrocenyl-6-methyl-pyrimidine were determined by X-ray analysis of suitable single crystals.

【 授权许可】

Unknown