Three-Component Reaction of Tautomeric Amidines with 3-Ferrocenylmethylidene-2,4-pentanedione. Formation of Polymeric Coordination Complexes of Potassium Ferrocenyl-(hexahydro)pyrimidoxides

Molecules

Elena I. Klimova¹  Marcos Flores-Alamo¹  Tatiana Klimova¹  Sandra Cortez Maya¹ 

[1] Facultad de Química, Universidad Nacional Autónoma de México, Cd. Universitaria, Coyoacán, C.P. 04510, México D.F., Mexico

关键词: ferrocene;    3-ferrocenylmethylidene-2;    4-pentanedione;    amidines;    ferrocenyl-pyrimidines;    ferrocenylpiperidones;    complexes of potassium ferrocenyl(hexahydro)-pyramidin-4-oxides;   

DOI  :  10.3390/molecules19010041

来源: mdpi

【 摘 要 】

Acetamidine hydrochloride and p-aminobenzamidine dihydrochloride interact with 3-ferrocenylmethylidene-2,4-pentanedione at 80–82 °C in the presence of K₂CO₃ in the water–alcohol medium in two tautomeric forms (the amidoimine and enediamine ones) with formation of mixtures of pyrimidine and piperidone derivatives and polymeric coordination complexes of potassium ferrocenyl(hexahydro)pyrimidoxides. The structure of the resultant compounds is elucidated on the basis of IR, ¹H- and ¹³C-NMR spectroscopy, mass spectrometry and elemental analysis data. The crystal structures of 6-ferrocenyl-4-hydroxy-4-methyl-2-piperidone, potassium 6-ferrocenyl-4-methyl-2-methylidene(hexahydro)pyrimidin-4-oxide and 2-(4-aminophenyl)-4-ferrocenyl-6-methyl-pyrimidine were determined by X-ray analysis of suitable single crystals.

【 授权许可】

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