SARS-CoV-2 Seroprevalence in Western Romania, March to June 2021

Medicina

卷:58

Alina Cristiana Craciun¹  Daliborca Cristina Vlad²  Victor Dumitrascu²  Tudor Rares Olariu³  Maria Alina Lupu³  Iosif Marincu³ 

[1] Clinical Laboratory, Municipal Clinical Emergency Teaching Hospital, 300254 Timisoara, Romania;

[2] Department of Biochemistry and Pharmacology, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania;

[3] Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania;

关键词: SARS-CoV-2;    antibodies;    COVID-19;    seroprevalence;    epidemiology;    Romania;   

DOI  :  10.3390/medicina58010035

来源: DOAJ

【 摘 要 】

Background and Objectives: The extent of SARS-CoV-2 infection among a population may be assessed by the presence of serum SARS-CoV-2 antibodies, which indicates previous exposure. The aim of this study was to determine the seroprevalence of SARS-CoV-2 infection in the adult population from Western Romania. Materials and Methods: Samples of 2443 consecutive individuals, referred for routine laboratory investigations, were tested for SARS-CoV-2 antibodies using the Elecsys immunoassay that targets the nucleocapsid protein, for identifying the presence of the total antibodies against SARS-CoV-2. Results: The overall SARS-CoV-2 seroprevalence was 45.60%. SARS-CoV-2 seroprevalence was significantly higher in age group 30–49 years (53.94%) compared to age groups 50–69 years (43.53%) and 70–91 years (30.79%) (p < 0.001, p < 0.001, respectively). No significant difference in seroprevalence was observed between females (44.83%) and males (47.05%). Conclusions: Our data revealed a high seroprevalence of SARS-CoV-2 infection in the adult population from Western Romania and indicate the rapid and significant spread of the virus. The estimated prevalence of 45.60% was 6 times higher than the rate of confirmed COVID-19 cases reported in the study area. This indicates the magnitude of virus transmission in the community.

【 授权许可】

Unknown