Native glycan fragments detected by MALDI mass spectrometry imaging are independent prognostic factors in pancreatic ductal adenocarcinoma

EJNMMI Research

Marija Trajkovic-Arsic¹  Corinna Münch¹  Jens T. Siveke¹  Irene Esposito²  Katja Steiger³  Anna Melissa Schlitter³  Wilko Weichert⁴  Na Sun⁵  Yin Wu⁵  Thomas Kunzke⁵  Annette Feuchtinger⁵  Fengxia Li⁵  Axel Walch⁵ 

[1] Bridge Institute of Experimental Tumor Therapy, West German Cancer Center, University Hospital Essen, 45147, Essen, Germany;Division of Solid Tumor Translational Oncology, German Cancer Consortium (DKTK, Partner Site Essen) and German Cancer Research Center, DKFZ, Heidelberg, Germany;Institute for Pathology, University Hospital Düsseldorf, Heinrich-Heine University, Düsseldorf, Germany;Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany;Member of the German Cancer Consortium (DKTK), Partner Site, Munich, Germany;Institute of Pathology, TUM School of Medicine, Technical University of Munich, Munich, Germany;Member of the German Cancer Consortium (DKTK), Partner Site, Munich, Germany;Comprehensive Cancer Center Munich (CCCM), Munich, Germany;Research Unit Analytical Pathology, Helmholtz Zentrum Munich, 85764, Neuherberg, Germany;

关键词: MALDI-FT-ICR-MSI;    Glycans;    PDAC;   

DOI  :  10.1186/s13550-021-00862-y

来源: Springer

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