A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis

BMC Neurology

Simon M. Durkin¹  Tumena W. Corrah¹  Junko Takata¹  Solomon Wong²  Michael S. Zandi³  Josephine K. Swanton⁴ 

[1] Department of Infectious Diseases and Tropical Medicine, Northwick Park Hospital, London North West University Healthcare NHS Trust, Watford Road, HA1 3UJ, Harrow, UK;Harrow Crisis Team, Central and North West London NHS Foundation Trust, Northwick Park Hospital, HA1 3UJ, Harrow, London, UK;National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, WC1N 3BG, London, UK;National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, WC1N 3BG, London, UK;Department of Neurology, Northwick Park Hospital, London North West University Healthcare NHS Trust, Watford Road, HA1 3UJ, Harrow, UK;

关键词: COVID-19;    Prevention & control (PC);    Encephalitis;    SARS-CoV-2;    Vaccination;    Adverse effects (AE);   

DOI  :  10.1186/s12883-021-02517-w

来源: Springer

【 摘 要 】

BackgroundVaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis.Case presentationA young woman presented with acute neuropsychiatric symptoms following recent ChAdOx1 nCoV-19 vaccination. Extensive investigation did not identify alternative causes.ConclusionsThis difficult case is here described, including presentation, investigation, and management. Further study on neuropsychiatric side-effects of COVID-19 vaccination, including investigation as to whether there may be a causal link, is required.

【 授权许可】

CC BY