α‐Synuclein antisense transcript SNCA‐AS1 regulates synapses‐ and aging‐related genes suggesting its implication in Parkinson's disease

Aging Cell

Stephana Carelli¹  Federica Rey¹  Rossella Launi¹  Gian Vincenzo Zuccotti²  Letizia Messa³  Bianca Barzaghini³  Manuela Teresa Raimondi³  Stella Gagliardi⁴  Cristina Cereda⁴  Cecilia Pandini⁵  Roberta Zangaglia⁶ 

[1] Department of Biomedical and Clinical Sciences "L. Sacco", University of Milan, Milan, Italy;Pediatric Clinical Research Center Fondazione “Romeo ed Enrica Invernizzi”, University of Milan, Milan, Italy;Department of Biomedical and Clinical Sciences "L. Sacco", University of Milan, Milan, Italy;Pediatric Clinical Research Center Fondazione “Romeo ed Enrica Invernizzi”, University of Milan, Milan, Italy;Department of Pediatrics, Children's Hospital "V. Buzzi", Milan, Italy;Department of Chemistry, Materials and Chemical Engineering, Politecnico di Milano, Milan, Italy;Genomic and post‐Genomic Center, IRCCS Mondino Foundation, Pavia, Italy;Genomic and post‐Genomic Center, IRCCS Mondino Foundation, Pavia, Italy;Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, Pavia, Italy;Parkinson's Disease and Movement Disorders Unit, IRCCS Mondino Foundation, Pavia, Italy;

关键词: aging;    LncRNAs;    Parkinson's disease;    RNA‐sequencing;    SNCA;    SNCA‐AS1;    synapses;    synuclein;   

DOI  :  10.1111/acel.13504

来源: Wiley

【 授权许可】

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