International Journal of Emergency Medicine | |
A peculiar case of psychosis: anti-NMDAr encephalitis | |
Lamia Kouba1  Dalia Alhosain2  | |
[1] Department of Dermatology, Damascus University Hospitals, Damascus, Syria;Department of Internal Medicine, Damascus University Hospitals, Damascus, Syria; | |
关键词: Anti-NMDA receptor encephalitis; Herpes simplex virus; Psychosis; Pregnancy; Case report; | |
DOI : 10.1186/s12245-021-00389-y | |
来源: Springer | |
【 摘 要 】
BackgroundPsychosis in pregnancy is rare and could be life-threatening. It requires prompt evaluation and proper management accordingly. Anti-N-methyl-d-aspartate receptor (anti-NMDAr) encephalitis following herpes simplex virus (HSV) infection is a rare cause of psychosis during pregnancy.Case presentationA 20-year-old woman at 18 weeks gestation presented with agitation and a 3-day history of hallucinations. She had a prior hospitalization for HSV encephalitis 6 weeks before. Her laboratory workup was unremarkable except for positive anti-NMDAr antibodies in the CSF. The patient was treated with high-dose corticosteroids and plasmapheresis, and she was discharged 2 weeks later fully recovered.ConclusionsAnti-NMDAr encephalitis can be the culprit behind a new-onset of psychosis in pregnancy. Early diagnosis and treatment are crucial.
【 授权许可】
CC BY
【 预 览 】
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