A Prediction Model for High Risk of Positive RT-PCR Test Results in COVID-19 Patients Discharged From Wuhan Leishenshan Hospital, China

Frontiers in Public Health

Kun Li¹  Yawei Qian²  Guang Zeng³  Limao Zhang⁴  Yang Liu⁵  Yue Pan⁶ 

[1] Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China;Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China;Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China;Leishenshan Hospital, Wuhan, China;Department of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China;Leishenshan Hospital, Wuhan, China;Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China;School of Civil and Environmental Engineering, Nanyang Technological University, Singapore, Singapore;School of Economics and Management, Wuhan University, Wuhan, China;Zhongnan Hospital of Wuhan University, Wuhan, China;School of Naval Architecture, Ocean & Civil Engineering, Shanghai Jiao Tong University, Shanghai, China;

关键词: COVID-19;    recovered;    patients;    nucleic acid;    re-detectable;    predict;    model;   

DOI  :  10.3389/fpubh.2021.778539

来源: Frontiers

【 摘 要 】

Several recent studies have reported that a few patients had positive SARS-CoV-2 RNA tests after hospital discharge. The high-risk factors associated with these patients remain to be identified. A total of 463 patients with COVID-19 discharged from Leishenshan Hospital in Wuhan, China, between February 8 and March 8, 2020 were initially enrolled, and 351 patients with at least 2 weeks of follow-up were finally included. Seventeen of the 351 discharged patients had positive tests for SARS-CoV-2 RNA. Based on clinical characteristics and mathematical modeling, patients with shorter hospital stays and less oxygen desaturation were at higher risk of SARS-CoV-2 RNA reoccurrence after discharge. Notably, traditional Chinese medicine treatment offered extensive benefits to reduce risk. Particular attention should be paid to those patients with high risk, and traditional Chinese medicine should be advocated.

【 授权许可】

CC BY