A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report

BMC Infectious Diseases

Yulin Zhang¹  Xue Chen¹  Yongfeng Wu¹  Yingmin Ma¹  Lin Jia¹  Tong Zhang¹  Jing Chang² 

[1] Department of Respiratory and Infectious Diseases, Beijing You An Hospital, Capital Medical University, Beijing Institute of Hepatology, 100069, Beijing, China;Pathology Diagnostic Center, Beijing You An Hospital, Capital Medical University, Beijing Institute of Hepatology, 100069, Beijing, China;

关键词: Talaromyces marneffei;    HIV;    AIDS;    Upper abdominal mass;    Next-generation sequencing;   

DOI  :  10.1186/s12879-021-06489-7

来源: Springer

【 摘 要 】

BackgroundAn upper abdominal mass without tenderness often indicates a benign or malignant tumor once liver or spleen hyperplasia has been excluded. A lymphadenopathic mass from Talaromyces marneffei infection is rare.Case presentationWe report the case of a 29-year-old human immunodeficiency virus (HIV) infected man who presented with an upper abdominal mass and without any symptoms related with infection. Histopathology and next-generation sequencing (NGS) following biopsy of the mass confirmed T. marneffei-infected lymphadenopathy, and the patient was successfully treated with amphotericin B and itraconazole.ConclusionsThis case report suggests that potential fungal infection should be considered during the diagnostic workup of a mass in clinical practice.

【 授权许可】

CC BY