Sudden Cardiac Death—A New Insight Into Potentially Fatal Genetic Markers

Frontiers in Medicine

article

Dragan Primorac¹  Swaroop Aradhya²  Tanja Sofrenović²  Vid Matišić¹  Vilim Molnar¹  Andrea Skelin¹  Jure Mirat⁶  Johannes Brachmann⁴  Ljubica Odak¹  Vitorio Perić¹  Jasmina Ćatić¹  Jozica Šikić^1,12  Vjekoslav Radeljić^1,13  Šime Manola^1,13  Robert Nussbaum²  Matteo Vatta² 

[1] St. Catherine Specialty Hospital;Eberly College of Science, The Pennsylvania State University, University Park, State College, United States;The Henry C. Lee College of Criminal Justice and Forensic Sciences, University of New Haven, United States;Medical School, University of Split;Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek;Faculty of Medicine, Josip Juraj Strossmayer University of Osijek;Medical School, University of Rijeka;Medical School REGIOMED;Medical School, University of Mostar;Children's Hospital Zagreb;Department of Cardiology, Clinical Hospital Dubrava;Department of Cardiology, Clinical Hospital Sveti Duh;Department of Cardiology, Clinical Hospital Center Sestre Milosrdnice

关键词: sudden cardiac death;    genes;    coronary artery disease;    cardiomyopathy;    professional athletes;   

DOI  :  10.3389/fmed.2021.647412

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Sudden cardiac death (SCD) is an unexpected and dramatic event. It draws special attention especially in young, seemingly healthy athletes. Our scientific paper is based on the death of a young, 23-year-old professional footballer, who died on the football field after a two-year history of cardiac symptoms. In this study we analyzed clinical, ECG and laboratory data, as well as results of genetic testing analysis in family members. To elucidate potential genetic etiology of SCD in this family, our analysis included 294 genes related to various cardiac conditions.

【 授权许可】

CC BY