The Journal of Veterinary Medical Science | |
Isolation of Streptococcus cuniculi from corneal lesion in laboratory-raised mice | |
article | |
Vunjia TIONG1  Sazaly ABUBAKAR1  Shih-Keng LOONG1  Haryanti Azura MOHAMAD WALI3  Kim-Kee TAN1  Pui-Fong JEE2  Fang-Shiang LIM1  Jing-Jing KHOO1  Pooi-Fong WONG3  Li-Yen CHANG2  | |
[1] Tropical Infectious Diseases Research & Education Centre, University of Malaya;Department of Medical Microbiology, Faculty of Medicine, University of Malaya;Animal Experimental Unit, Faculty of Medicine, University of Malaya;Department of Pharmacology, Faculty of Medicine, University of Malaya | |
关键词: eye; infectious disease; laboratory mouse; Streptococcus cuniculi; | |
DOI : 10.1292/jvms.20-0070 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
Corneal lesions appearing as white mass beneath intact epithelium, with ocular discharge in one mouse, was observed in a batch of laboratory-raised BALB/c mice (n=9 of 56). The affected mice remained active, well-groomed and had normal appetite. Isolates recovered from swab cultures of the external and internal contents of the eye had partial 16S rRNA gene sequence of 99.1% similarity to Streptococcus cuniculi . No previous report of S . cuniculi infection in laboratory rodents has been presented. The isolate was susceptible to all antibiotics tested. We suggest S . cuniculi is an opportunistic bacteria in laboratory mice but are uncertain of its source. Our findings revealed that S. cuniculi is able to colonize laboratory mice and should be considered when mice present with eye lesion or ocular discharge.
【 授权许可】
Unknown
【 预 览 】
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