Factors associated with latent tuberculosis among international migrants in Brazil: a cross-sectional study (2020)

BMC Infectious Diseases

Vania Maria Silva Araujo¹  Keila Cristina Mascarello²  Nahari de Faria Marcos Terena³  Maysa Mabel Fauth⁴  Ethel Leonor Noia Maciel⁴  Sonia Vivian de Jezus⁴  Carolina Maia Martins Sales⁴  Thiago Nascimento do Prado⁴  Ricardo Alexandre Arcêncio⁵  Miguel Angel López Aragón⁶  Raphael Florindo Amorim⁷ 

[1] Brazilian TB Research Network, REDE-TB, Rio de Janeiro, Brazil;Department of Health Sciences, Centro Universitário Norte do Espírito Santo, Universidade Federal do Espírito Santo, São Mateus, ES, Brazil;Department of Statistics, University of Rome La Sapienza, Rome, Italy;Epidemiology Laboratory, Universidade Federal do Espírito Santo, Vitória, ES, Brazil;Graduate Studies Program in Public Health Nursing, Universidade de São Paulo, Escola de Enfermagem de Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil;Pan-American Health Organization, Washington, USA;Universidade Federal de Roraima, Undergraduate Course in Nursing, Boa Vista, RR, Brazil;

关键词: Tuberculosis;    International migrants;    Society for the Reception of migrants;    Latent tuberculosis;    Refugee camps;    Observational study;   

DOI  :  10.1186/s12879-021-06227-z

来源: Springer

【 摘 要 】

BackgroundMigrants are a high priority group for TB control measures due to their high exposure to risk factors such as poverty and social vulnerability. The study aimed to identify factors associated with latent TB among international migrants living in four Brazilian state capitals.MethodsThis was a cross-sectional study conducted in September and October 2020 in a sample of 903 international migrants living in four Brazilian state capitals: Boa Vista/RR (458), Manaus/AM (136), São Paulo/SP (257), and Curitiba/PR (52). Data were collected with a questionnaire consisting of open and closed questions on personal characteristics, information on TB, and use of preventive measures. Tuberculin skin test (TST) was performed, with reading after 72 h by trained nurses and using 5 mm induration as the positive cutoff. Chi-square test (X2) and Fisher's exact test, both two-tailed, were used to compare statistically significant levels of association between the migrants´ sociodemographic characteristics, vulnerability, and latent TB infection (LTBI). Binary logistic regression was applied to calculate odds ratios and respective 95% confidence intervals. For all the tests, type I error of 5% was defined as statistically significant (p < 0.05).ResultsPrevalence of LTBI among migrants was 46.1% in Manaus/AM, 33.3% in São Paulo/SP, 28.1% in Curitiba/PR, and 23.5% in Boa Vista/RR. Factors associated with latent infection were age, male gender, and brown or indigenous race.ConclusionsThe study showed high prevalence of latent TB among international migrants.

【 授权许可】

CC BY