Anti-nutritional characteristics and mechanism of soybean agglutinin

Biocell

article

LI PAN¹  JIAWEI LIU²  MOHAMMED HAMDY FAROUK¹  GUIXIN QIN¹  NAN BAO¹  YUAN ZHAO¹  HUI SUN¹ 

[1] Key Laboratory of Animal Production, Ministry of Education, Key Laboratory of Animal Nutrition and Feed Science, College of Animal Science and Technology, Jilin Agricultural University;Animal Production Department, Faculty of Agriculture, Al-Azhar University

关键词: Soybean agglutinin;    Autophagy;    Cell apoptosis;    Anti-nutritional functions;    Cell signaling;   

DOI  :  10.32604/biocell.2021.014289

学科分类：仪器

来源: Biocell

【 摘 要 】

Soybean agglutinin (SBA) is an important anti-nutritional factor in soybean. SBA can induce animal growth inhibition, cause pathological changes of intestinal tissue, and decrease in the immune system functioning. Recently, a great deal of research has been done on the effects of SBA on cell morphology, division, apoptosis, autophagy, as well as the correlated signal transduction pathway. This review mainly covers the chemical and biological characteristics of SBA, describes the multifaceted aspects of SBA anti-nutritional functions, and highlights the possible cellular and molecular mechanism of anti-nutritional effects of SBA. This review has important implications for the prevention and treatment of SBA-induced diseases, drug development, processing techniques of plant products, prevention of food- borne toxins, as well as human and animal health protection.

【 授权许可】

CC BY