Functional Surfactants for Molecular Fishing, Capsule Creation, and Single-Cell Gene Expression

Nano-Micro Letters

Leila Amini¹  Michael Schmueck-Henneresse¹  Mohammad Suman Chowdhury²  Pradip Dey²  Abhishek Kumar Singh²  Abbas Faghani²  Rainer Haag²  Xingcai Zhang³ 

[1] Berlin Institute of Health – Center for Regenerative Therapies, Charité Universitätsmedizin Berlin – CVK, Föhrer Str. 15, 13353, Berlin, Germany;Berlin Center for Advanced Therapies, Charité Universitätsmedizin Berlin – CVK, Föhrer Str. 15, 13353, Berlin, Germany;Institut Für Chemie Und Biochemie, Freie Universität Berlin, Takustrasse 3, 14195, Berlin, Germany;John A. Paulson School of Engineering and Applied Sciences, Harvard University, 02138, Cambridge, MA, USA;School of Engineering, Massachusetts Institute of Technology, 02139, Cambridge, MA, USA;

关键词: Dendronized fluorosurfactants;    Droplet microfluidics;    Microcapsules;    Oxidation-responsive fluorosurfactants;    Cell encapsulation;   

DOI  :  10.1007/s40820-021-00663-x

来源: Springer

【 摘 要 】

tsWe have demonstrated how to create a parent surfactant that is open to manipulation, while maintaining its surface activity, robustness, and compatibility, to expand the landscape of surfactant-dependent microfluidic-droplet-based assays.To create a library of functional surfactants from the parent surfactant, an oxidation-responsive small building block with thioethers and multiple 1,2-diols was used as a head group, while a non-polar perfluoropolyether chain was used as a tail.

【 授权许可】

CC BY