Iron-Imprinted Single-Atomic Site Catalyst-Based Nanoprobe for Detection of Hydrogen Peroxide in Living Cells

Nano-Micro Letters

Xiaoqing Pan¹  Zhenxing Feng²  Maoyu Wang²  Dan Du³  Shichao Ding³  Zhaoyuan Lyu³  Chengzhou Zhu³  Yuehe Lin³  Hangyu Tian³ 

[1] Irvine Materials Research Institute (IMRI), University of California, 92697, Irvine, CA, USA;School of Chemical, Biological, and Environmental Engineering, Oregon State University, 97331, Corvallis, OR, USA;School of Mechanical and Materials Engineering, Washington State University, 99164, Pullman, WA, USA;

关键词: Single-atomic site catalysts;    Nanoprobe;    Peroxidase-like activities;    Biosensing;    Living cell;   

DOI  :  10.1007/s40820-021-00661-z

来源: Springer

【 摘 要 】

tsA facile ion-imprinting method (IIM) is used to synthesize the isolated Fe-N-C single-atomic site catalyst (IIM-Fe-SASC), which mimics the natural enzyme-like active site and shows excellent peroxidase-like activity.The ion-imprinting process can precisely control ion at the atomic level and form numerous well-defined single-atomic Fe-N-C sites.The IIM-Fe-SASC has been successfully used as the nanoprobe for in situ H2O2 detection generated from MDA-MB-231 cells.

【 授权许可】

CC BY