Two-dimensional MXene-based materials for photothermal therapy

Nanophotonics

article

Zhongming Huang¹  Xiao Cui¹  Shengliang Li¹  Jinchao Wei²  Peng Li²  Yitao Wang²  Chun-Sing Lee¹ 

[1] Center of Super-Diamond and Advanced Films (COSDAF) and Department of Chemistry, City University of Hong Kong;Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau;Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University

关键词: MXenes;    two-dimensional materials;    photothermal therapy;    synergistic therapy;   

DOI  :  10.1515/nanoph-2019-0571

学科分类：社会科学、人文和艺术（综合）

来源: De Gruyter

【 摘 要 】

MXenes, a new family of two-dimensional materials, are also known as transition metal carbides and nitride, with a general formula of M n +1 X n T x ( n  = 1–3). Their inherent metallic conductivity and hydrophilic nature endow MXenes with fascinating physicochemical properties (optical, electronic, magnetic, light-to-heat conversion. etc.). The ultrathin layer structure and photothermal property attract many interests in biomedical applications, especially as phototherapeutic agents for cancer treatment. In this review, we summarize the recent progress of MXenes in the field of photothermal therapy and highlight the crucial biotic index for their preparation and evaluation. First, we introduce the main strategies for the preparation and surface modifications of biologically applied MXenes. Then, representative cases in the field of MXene-based photothermal application, such as photothermal therapy, synergistic therapy, and targeting treatments, are reviewed. Finally, the cytotoxicity and in vivo long-term biosafety are introduced. We also propose the underlying challenges and perspectives for MXene applications in terms of photothermal therapy.

【 授权许可】

CC BY