Chemiluminescent carbon nanodots as sensors for hydrogen peroxide and glucose

Nanophotonics

article

Cheng-Long Shen¹  Chong-Xin Shan¹  Guang-Song Zheng¹  Meng-Yuan Wu¹  Jian-Yong Wei¹  Qing Lou¹  Yang-Li Ye¹  Zhi-Yi Liu¹  Jin-Hao Zang¹  Lin Dong¹ 

[1] Henan Key Laboratory of Diamond Optoelectronic Materials and Devices, Key Laboratory of Materials Physics, Ministry of Education, and School of Physics and Microelectronics, Zhengzhou University

关键词: carbon nanodots;    chemiluminescence;    glucose;    hydrogen peroxide;    sensor;   

DOI  :  10.1515/nanoph-2020-0233

学科分类：社会科学、人文和艺术（综合）

来源: De Gruyter

【 摘 要 】

Hydrogen peroxide (H 2 O 2 ) is an important product generated in the body and related to many pathophysiological processes and glucose metabolism disorder can cause many fatal diseases in living bodies. Therefore, the sensing of H 2 O 2 and glucose is of great significance in disease diagnostics and treatment. Fluorescent carbon dots (CDs) are one new class of nanoprobes for H 2 O 2 and glucose. Nevertheless, the CD-based sensor is always based on its fluorescence response, which is influenced by the auto-fluorescent interference. Herein, efficient fluorescent CDs were synthesized by one-pot solvothermal method, and the CDs exhibit bright and persistent deep-red (DR) chemiluminescence (CL) in bis(2,4,6-trichlorophenyl) oxalate and H 2 O 2 solution with a CL quantum yield of (8.22 ± 0.30) × 10 −3 , which is amongst the highest values in ever reported nanomaterials for chemical analysis. Employing the CDs as CL nanoprobes, sensitive sensing for H 2 O 2 has been achieved with a detection limit of 11.7 μM, and further for glucose detection with a detection limit of 12.6 μM. The DR CL CDs is promising to be applied in blood glucose analysis or in vivo biosensor.

【 授权许可】

CC BY